Monofilament is made entirely out of the same polymer; copolymer is made out of 2 or more (usually 2) polymers. Copolymer allows you to make a core of very limp line and then coat it with a tougher, more abrasion resistant polymer to get the best of both worlds. Like mono, some are good and some are bad. P-Line CXX is an awesome copolymer.